Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL17784233 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Bicarbonate SCHEMBL934383 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL7052291 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclopentane SCHEMBL8102000 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL9754177 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL168638 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Bicarbonate SCHEMBL7521496 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL8160484 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL3406024 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 | |
| Cyclohexane SCHEMBL25742 | 1.00 | CA1 (0.62) | CA1CA2CA9FFAR3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791614-B1 | Use of urethanised polyester as an additive for aqueous coating compositions | BASF COATINGS AG (DE) | 2004-04-21 | — | — | EP | claimed |
| EP-0776920-B1 | Polyester-acrylate based binder, process for its preparation and its use | SYNTHOPOL CHEMIE DR KOCH (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-0883640-B1 | NOVEL POLYESTER POLYOLS AND THEIR USE AS THE POLYOL COMPONENT IN TWO-COMPONENT POLYURETHANE PAINTS | SYNTHOPOL CHEMIE DR KOCH (DE) | 1999-08-18 | — | — | EP | claimed |
| EP-0791614-A1 | Urethanised polyester as an additive for aqueous coating compositions | BASF Lacke + Farben AG (DE) | 1997-08-27 | — | — | EP | claimed |
| EP-0776920-A2 | Polyester-acrylate based binder, process for its preparation and its use | SYNTHOPOL CHEMIE Dr. rer. pol. Koch GmbH & CO. KG (DE) | 1997-06-04 | — | — | EP | claimed |
| EP-3230336-B1 | AQUEOUS POLYURETHANE-POLYUREA DISPERSION AND AQUEOUS BASE COAT CONTAINING THE DISPERSION | BASF COATINGS GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| EP-3292164-B1 | METHOD FOR PRODUCING A MULTILAYER COATING | BASF COATINGS GMBH (DE) | 2021-12-08 | — | — | EP | disclosed |
| EP-3484936-B1 | AQUEOUS BASE COAT AND PRODUCTION OF MULTILAYER COATINGS USING THE BASE COAT | BASF COATINGS GMBH (DE) | 2021-09-08 | — | — | EP | disclosed |
| EP-3873959-A1 | MULTI-LAYER PAINT STRUCTURE WITH IMPROVED LAYER ADHESION | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-09-08 | — | — | EP | disclosed |
| EP-3371240-B1 | WÄSSRIGE BASISLACKE ENTHALTEND VERNETZTE POLYURETHAN-BINDEMITTEL SOWIE EINE SPEZIELLE LÖSEMITTELZUSAMMENSETZUNG | BASF COATINGS GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |
| EP-3298059-B1 | METHOD FOR PRODUCING A MULTILAYER COATING | BASF COATINGS GMBH (DE) | 2021-06-09 | — | — | EP | disclosed |
| EP-3297773-B1 | AQUEOUS BASE PAINT FOR MAKING A COATING | BASF COATINGS GMBH (DE) | 2021-06-09 | — | — | EP | disclosed |
| WO-1990001507-A1 | MOISTURE-CURING HOT-MELT ADHESIVES CONTAINING TERMINAL ALKOXYSILANE GROUPS AND THEIR USE AS ADHESIVES AND SEALANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-02-22 | — | — | WO | disclosed |
| EP-0354472-A1 | Alkoxysilane-terminated moisture-curable hot melt adhesives and their use as adhesive and sealant masses | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-02-14 | — | — | EP | disclosed |
| EP-0129813-B1 | COATING PREPARATION PROCESS | BASF Aktiengesellschaft (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0129813-A2 | Coating preparation process | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | disclosed |
| EP-0036975-B1 | METHOD OF MAKING METAL EFFECT LACQUERS AND FLAT ARTICLES PROVIDED WITH WEATHERRESISTANT METAL EFFECT MULTILAYERED LACQUERS | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |
| EP-0003966-B1 | SEVERAL LAYERS OF LACQUER COATED BY A TRANSPARENT LACQUER AND PROCESS FOR THE PREPARATION THEREOF | BASF Lacke + Farben AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| EP-0036975-A2 | Method of making metal effect lacquers and flat articles provided with weatherresistant metal effect multilayered lacquers | BAYER AG (DE) | 1981-10-07 | — | — | EP | disclosed |
| EP-0003966-A1 | Several layers of lacquer coated by a transparent lacquer and process for the preparation thereof | BASF Lacke + Farben AG (DE) | 1979-09-19 | — | — | EP | disclosed |