Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527466 | 1.00 | KDM1A (0.61) | KDM1AMAOBMAOA | |
| SCHEMBL18949355 | 0.84 | KDM1A (0.67) | KDM1AMAOBMAOA | |
| SCHEMBL16221033 | 0.83 | KDM1A (0.66) | KDM1AMAOBMAOA | |
| SCHEMBL6837439 | 0.81 | KDM1A (0.74) | KDM1AMAOBMAOA | |
| SCHEMBL527335 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL527334 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL7692647 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL528178 | 0.76 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL527600 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL526980 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |