Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.33 |
| ▸ | GABRE | P78334 | 3/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420268 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14420361 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL598013 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL52746 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13502497 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13502491 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5516743 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4965400 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3574366 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL599279 | 1.00 | SLC7A5 (0.57) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116549428-B | New application of 4-hydroxyisoleucine | 郑州大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119775234-A | Compound with plant growth regulation effect and preparation method and application thereof | 北京中医药大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119745855-A | Application of alpha-ketoglutarate substance in preparation of medicine for treating fetal intrauterine growth restriction | 安徽医科大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119454684-A | Application of 4-hydroxyisoleucine in preparation of medicine for treating atherosclerosis | 杨朝晖 | 2025-02-18 | — | — | CN | claimed |
| CN-118125936-A | N-acyl ethanolamide derivative, preparation method and application thereof | 南京清普生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117866861-A | Genetically engineered bacterium for producing 4-hydroxyisoleucine and application thereof | 无锡晶海氨基酸股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117388421-A | Method for identifying forage grass rhizosphere secretion and differential metabolite thereof based on non-targeted metabonomics | 中国农业大学 | 2024-01-12 | — | — | CN | claimed |
| CN-116870038-A | Post-natal powder of lactobacillus plantarum J26 and application of post-natal powder in aspect of cholesterol reduction | 东北农业大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114480466-B | Dynamic regulation bacterium for producing 4-hydroxyisoleucine and application thereof | 江南大学 | 2023-08-25 | — | — | CN | claimed |
| CN-116549428-A | New application of 4-hydroxyisoleucine | 郑州大学 | 2023-08-08 | — | — | CN | claimed |
| CN-1397545-A | A method for extracting 4-hydroxy-isoleucine and fenugreek gum from semen Trigonellae | YINGHAN INTERNAT TRADE CO LTD (CN) | 2003-02-19 | — | — | CN | claimed |
| EP-1053232-B1 | PROCESS FOR THE PREPARATION OF SOTOLON | UNILEVER NV (NL) | 2002-11-06 | — | — | EP | claimed |
| CN-1376062-A | Use of amino acids for making medicine for treating to insulin-resistance | INNODIA S A (FR) | 2002-10-23 | — | — | CN | claimed |
| EP-1206257-A1 | USE OF AMINO ACIDS FOR MAKING MEDICINES FOR TREATING INSULIN-RESISTANCE | Innodia (FR) | 2002-05-22 | — | — | EP | claimed |
| CN-1289329-A | Process for preparing SOTOLON | UNILEVER NV (NL) | 2001-03-28 | — | — | CN | claimed |
| WO-2001015689-A1 | USE OF AMINO ACIDS FOR MAKING MEDICINES FOR TREATING TO INSULIN-RESISTANCE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-03-08 | — | — | WO | claimed |
| EP-0587476-B1 | Compositions containing mono or polyhydroxylated amino acids for the treatment of non-insulin dependent diabetes mellitus | JOUVENET SOC CIV (FR) | 1998-03-18 | — | — | EP | claimed |
| WO-1997032577-A1 | ANTIDIABETIC COMPOSITION CONTAINING (2S, 3R, 4S)4-HYDROXYISOLEUCINE | SOCIETE CIVILE DE GESTION JOUVENET (FR) | 1997-09-12 | — | — | WO | claimed |
| US-5470879-A | 4-hydroxyisoleucine or lactone thereof | LABORATORIES MONAL (FR) | 1995-11-28 | — | — | US | claimed |
| EP-0587476-A1 | Compositions containing mono or polyhydroxylated amino acids for the treatment of non-insulin dependent diabetes mellitus | Société Civile JOUVENET (FR) | 1994-03-16 | — | — | EP | claimed |