Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.62 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277975 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3521056 | 0.91 | CALCRL (0.66) | CALCRLRAMP1 | |
| SCHEMBL3521059 | 0.91 | CALCRL (0.66) | CALCRLRAMP1 | |
| SCHEMBL4501726 | 0.89 | CALCRL (0.64) | CALCRLRAMP1 | |
| SCHEMBL4501729 | 0.89 | CALCRL (0.64) | CALCRLRAMP1 | |
| SCHEMBL13331914 | 0.87 | CALCRL (0.73) | CALCRLRAMP1 | |
| SCHEMBL13331918 | 0.87 | CALCRL (0.75) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL14375086 | 0.87 | CALCRL (0.69) | CALCRLRAMP1 | |
| SCHEMBL13331911 | 0.86 | CALCRL (0.74) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL13331917 | 0.86 | CALCRL (0.70) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863799-A1 | CGRP-ANTAGONISTS, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100009-A1 | CGRP ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |