Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19382438 | 0.86 | EPHX1 (0.40) | TSHREPHX1SLC18A3SIGMAR1MEN1 | |
| SCHEMBL3628911 | 0.77 | — | — | |
| SCHEMBL27655090 | 0.74 | TSHR (0.40) | TSHREPHX1SMN1; SMN2SLC18A3SIGMAR1 | |
| SCHEMBL24139390 | 0.74 | MEN1 (0.44) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1199046 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 | |
| SCHEMBL1103798 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 | |
| SCHEMBL270441 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 | |
| SCHEMBL63809 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 | |
| SCHEMBL12914371 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 | |
| SCHEMBL3644410 | 0.71 | EPHX1 (0.52) | TSHREPHX1MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858955-A1 | PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006091901-A1 | PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-08-31 | — | — | WO | disclosed |