SCHEMBL5279871 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.35

▸	CYP2C19	P33261	2/20	0.35

▸	POLB	P06746	1/20	0.35

▸	TOP2A	P11388	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.32

▸	SMN1; SMN2	Q16637	1/20	0.32

▸	MAPK14	Q16539	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5278527	0.78	TOP2A (0.36)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5281183	0.76	CYP1A2 (0.37)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5280069	0.74	CYP1A2 (0.40)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5275765	0.74	TOP2A (0.34)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5276571	0.73	CYP1A2 (0.35)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5284135	0.73	TOP2A (0.33)	CYP1A2CYP2C19TOP2AALDH1A1SMN1; SMN2
SCHEMBL5281331	0.73	TOP2A (0.37)	CYP1A2CYP2C19TOP2AALDH1A1SMN1; SMN2
SCHEMBL5281118	0.73	CYP1A2 (0.35)	CYP1A2CYP2C19POLBTOP2AALDH1A1
SCHEMBL5278236	0.72	TOP2A (0.31)	TOP2A
SCHEMBL5278790	0.72	CYP1A2 (0.33)	CYP1A2CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1859781-A2	Brightening and/or colouring agent with triazoles	Henkel Kommanditgesellschaft auf Aktien (DE)	2007-11-28	—	—	EP	disclosed