Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283385 | 1.00 | GAA (0.64) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL1863269 | 1.00 | GAA (0.64) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL5299387 | 1.00 | GAA (0.64) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL5287930 | 1.00 | GAA (0.64) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL573789 | 0.98 | GAA (0.61) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL4492849 | 0.94 | BTK (0.58) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL2074992 | 0.90 | GAA (0.51) | GAAEPHX1BTKCTSKCTSS | |
| Hydrochloric Acid SCHEMBL4657631 | 0.89 | GAA (0.52) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL14853197 | 0.84 | GAA (0.48) | GAAEPHX1BTKHDAC4HDAC1 | |
| SCHEMBL12276713 | 0.84 | GAA (0.48) | GAAEPHX1BTKHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |