Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 14/20 | 0.86 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.86 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.86 |
| ▸ | OXTR | P30559 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5094923 | 0.99 | AVPR1A (0.84) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL5284652 | 0.92 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2OXTR | |
| Hydrochloric Acid SCHEMBL5107962 | 0.92 | AVPR1A (0.98) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL5101530 | 0.91 | AVPR1A (0.70) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727555 | 0.90 | AVPR1A (0.84) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727593 | 0.89 | AVPR1A (0.86) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727425 | 0.89 | AVPR1A (0.86) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL20727409 | 0.89 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL5280988 | 0.88 | AVPR1A (0.85) | AVPR1AAVPR2KCNH2OXTR | |
| SCHEMBL5094865 | 0.88 | AVPR1A (0.84) | AVPR1AAVPR2KCNH2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656183-B1 | TREATMENT OF MALE SEXUAL DYSFUNCTION | PFIZER LTD (GB) | 2007-12-05 | — | — | EP | claimed |
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| WO-2004074291-A1 | TRIAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2004-09-02 | — | — | WO | disclosed |