SCHEMBL5280797

SCHEMBL5280797

Cn1nnc(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5277789 0.74
SCHEMBL5280319 0.72
SCHEMBL5279968 0.72
SCHEMBL5275782 0.69
SCHEMBL5276013 0.69
SCHEMBL5275220 0.69
SCHEMBL5284560 0.69
SCHEMBL5278474 0.69
SCHEMBL5282417 0.69
SCHEMBL5275707 0.69 POLB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024107658-A2 INHIBITORS OF TYK2 VYRNWY THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
WO-2024020034-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2024-01-25 WO disclosed
WO-2023249473-A1 ANTIBODY-DRUG CONJUGATE WITH TWO TYPES OF DRUG-LINKER CONJUGATES ON SINGLE ANTIBODY 주식회사 피노바이오 2023-12-28 WO disclosed
WO-2023245162-A2 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
WO-2023214849-A1 CONJUGATE OF DDX5 PROTEIN-BINDING CAMPTOTHECIN-BASED DRUG LINKED TO ACID-SENSITIVE LINKER AND IMMUNOCONJUGATE USING SAME 주식회사 피노바이오 2023-11-09 WO disclosed
EP-3356345-B1 HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS MAX PLANCK GESELLSCHAFT (DE) 2023-11-08 EP disclosed
US-20230339927-A1 ATR INHIBITORS AND USES THEREOF ANTENGENE DISCOVERY LIMITED (CN) 2023-10-26 US disclosed
US-20230339927-A1 ATR INHIBITORS AND USES THEREOF ANTENGENE DISCOVERY LIMITED (CN) 2023-10-26 US disclosed
WO-2023205778-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-26 WO disclosed
US-20230322745-A1 FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2023-10-12 US disclosed
US-20090004597-A1 Photosensitive Composition, Display Member, and Process for Producing The Same TORAY INDUSTRIES, INC. (JP) 2009-01-01 US disclosed
US-20090004597-A1 Photosensitive Composition, Display Member, and Process for Producing The Same TORAY INDUSTRIES, INC. (JP) 2009-01-01 US disclosed
US-20080312435-A1 Imine Compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-18 US disclosed
US-20080312435-A1 Imine Compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-18 US disclosed
US-7439253-B2 Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors NOVEXEL (FR) 2008-10-21 US disclosed
EP-1980910-A1 PHOTOSENSITIVE COMPOSITION, DISPLAY MEMBER, AND PROCESS FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2008-10-15 EP disclosed
US-20080177059-A1 FREE CHOLESTEROL ANALOGS BEARING A BORON DIPYRROMETHENE DIFLUORO (BODIPY) FLUOROPHORE IN THE SIDE CHAIN AND METHOD OF PREPARATION AND USE THEREOF RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK 2008-07-24 US disclosed
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed
US-7279470-B2 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2007-10-09 US disclosed
US-7235575-B2 Guanidine mimics as factor Xa inhibitors BRISTOL MYERS SQUIBB COMPANY (US) 2007-06-26 US disclosed