SCHEMBL5281506

SCHEMBL5281506

Cc1cc(NCCCCCCN2CCCCC2)c2ccccc2n1.Cc1cc(NCCCN2CCCCC2)c2ccccc2n1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 12/20 0.66
HRH3 Q9Y5N1 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491669 0.99 HRH3 (0.66) ACP1HRH3
SCHEMBL491641 0.96 ACP1 (0.70) ACP1HRH3
SCHEMBL5281218 0.87 HRH3 (0.76) HRH3
SCHEMBL5281041 0.87 HRH3 (0.76) HRH3
SCHEMBL6052727 0.87 HRH3 (0.76) HRH3
SCHEMBL7396965 0.86 HRH3 (0.75) HRH3
SCHEMBL22390054 0.84 CYP2C19 (0.73)
Quindecamine SCHEMBL2111177 0.84 CYP2C19 (0.73)
SCHEMBL5276042 0.84 HRH3 (0.65) ACP1HRH3
SCHEMBL5484741 0.83 HRH3 (0.62) ACP1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863486-A2 TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS BIOPROJET (FR) 2007-12-12 EP claimed
WO-2006103537-A2 TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS BIOPROJET (FR) 2006-10-05 WO claimed
EP-1100503-A2 NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS SOCIETE CIVILE BIOPROJET (FR) 2001-05-23 EP claimed
WO-2000006254-A2 NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H3-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS SOCIETE CIVILE BIOPROJET (FR) 2000-02-10 WO claimed