⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106136 | 0.74 | — | — | |
| SCHEMBL5274889 | 0.73 | — | — | |
| SCHEMBL5279806 | 0.73 | — | — | |
| SCHEMBL5280202 | 0.72 | — | — | |
| SCHEMBL5281195 | 0.72 | — | — | |
| SCHEMBL5278710 | 0.72 | — | — | |
| SCHEMBL5285225 | 0.69 | — | — | |
| SCHEMBL5280000 | 0.69 | — | — | |
| SCHEMBL5279542 | 0.69 | — | — | |
| SCHEMBL5279708 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240390340-A1 | PYRROLIDINE KRAS INHIBITORS | INCYTE CORP (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4389754-A1 | METAL-ORGANIC COORDINATION COMPOUND AND METHOD FOR PRODUCING THE SAME | beeOLED GmbH (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-9856259-B2 | Heterocyclic compounds and uses thereof | PLEXXIKON INC. (US) | 2018-01-02 | — | — | US | disclosed |
| WO-2017132617-A1 | ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20160075712-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PLEXXIKON INC. | 2016-03-17 | — | — | US | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |