Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281527 | 1.00 | MAPK1 (0.72) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL5281534 | 1.00 | MAPK1 (0.72) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL20006042 | 0.85 | MAPK1 (0.78) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18103079 | 0.85 | MAPK1 (0.78) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18102846 | 0.85 | MEN1 (0.67) | MAPTALDH1A1RAB9AMITFNCOA3 | |
| SCHEMBL15816994 | 0.84 | MAPK1 (1.00) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL15816991 | 0.84 | MAPK1 (1.00) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL15816995 | 0.84 | MAPK1 (1.00) | MAPK1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL18102932 | 0.84 | CISD1 (0.76) | MAPK1ALDH1A1KDM4ETDP1CISD1 | |
| SCHEMBL541143 | 0.83 | MAPT (0.89) | MAPTALDH1A1LMNAKDM4ECISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | disclosed |