Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 1.00 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5108492 | 0.99 | AVPR1A (0.98) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5108408 | 0.89 | AVPR1A (0.79) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5094839 | 0.88 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5094927 | 0.86 | AVPR1A (0.79) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5094751 | 0.86 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5098399 | 0.85 | AVPR1A (1.00) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL20727378 | 0.85 | AVPR1A (0.77) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5094904 | 0.84 | AVPR1A (0.75) | AVPR1AAVPR2KCNH2 | |
| SCHEMBL5281487 | 0.83 | AVPR1A (0.76) | AVPR1AAVPR2KCNH2 | |
| Hydrochloric Acid SCHEMBL5098224 | 0.82 | AVPR1A (0.75) | AVPR1AAVPR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656183-B1 | TREATMENT OF MALE SEXUAL DYSFUNCTION | PFIZER LTD (GB) | 2007-12-05 | — | — | EP | claimed |
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442795-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2008-10-28 | — | — | US | disclosed |
| WO-2004074291-A1 | TRIAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2004-09-02 | — | — | WO | disclosed |