Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711938 | 0.89 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL968932 | 0.89 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL12917170 | 0.89 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL5179063 | 0.89 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL15090843 | 0.85 | KDM4E (0.44) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL5277569 | 0.83 | KDM4E (0.49) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL6963050 | 0.83 | CYP3A4 (0.48) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL9236230 | 0.83 | CYP3A4 (0.41) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL5284692 | 0.83 | CYP3A4 (0.41) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL15062995 | 0.82 | KCNH2 (0.43) | KDM4EHPGDALDH1A1KCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |