SCHEMBL5282116

SCHEMBL5282116

CCCCc1nn[nH]c1C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.38
HCAR3 P49019 2/20 0.38
HRH3 Q9Y5N1 1/20 0.35
GAA P10253 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMPD3 Q9NY59 1/20 0.33
MAOB P27338 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600403 0.94 MEN1 (0.37) HCAR2HCAR3ALDH1A1MEN1KMT2A
SCHEMBL5601763 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5603213 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5600516 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5601887 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5600267 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5603360 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5601383 0.92 MEN1 (0.36) HCAR2HCAR3MAPTALDH1A1MEN1
SCHEMBL5277025 0.86
SCHEMBL5276698 0.78 HCAR2 (0.44) HCAR2HCAR3HRH3GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed