Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399792 | 0.97 | MAPK14 (0.56) | MAPK14CYP3A4CYP2C9 | |
| SCHEMBL1399813 | 0.93 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5282130 | 0.89 | MAPK14 (0.48) | MAPK14CYP3A4CYP2C9 | |
| SCHEMBL1399902 | 0.87 | GAA (0.44) | MAPK14CYP2C9 | |
| SCHEMBL1399718 | 0.82 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL1399883 | 0.81 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL1399809 | 0.81 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL1399884 | 0.79 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL1399977 | 0.79 | CNR2 (0.41) | MAPK14 | |
| SCHEMBL1399996 | 0.78 | MAPK14 (0.56) | MAPK14CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831174-A1 | AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006067444-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |