Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327196 | 0.84 | TSHR (0.63) | TSHRTHRBCA12CA1CA2 | |
| SCHEMBL18674241 | 0.80 | TSHR (0.65) | TSHRTHRBCA12CA1CA2 | |
| SCHEMBL9773059 | 0.80 | TSHR (0.56) | TSHRTHRBCA12CA1CA2 | |
| SCHEMBL10526650 | 0.79 | TSHR (0.69) | TSHRTHRBDNM1NAAAPOLB | |
| SCHEMBL12346282 | 0.79 | TSHR (0.69) | TSHRTHRBDNM1NAAAPOLB | |
| SCHEMBL6914198 | 0.79 | TSHR (0.69) | TSHRTHRBDNM1NAAAPOLB | |
| SCHEMBL2832317 | 0.79 | TSHR (0.69) | TSHRTHRBDNM1NAAAPOLB | |
| SCHEMBL1323804 | 0.79 | TSHR (0.69) | TSHRTHRBDNM1NAAAPOLB | |
| SCHEMBL5935872 | 0.78 | TSHR (0.67) | TSHRTHRBDNM1POLBAPEX1 | |
| SCHEMBL1326500 | 0.78 | TSHR (0.57) | TSHRTHRBCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | claimed |
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | disclosed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | disclosed |
| WO-2007002671-A1 | LAMINATED CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060290882-A1 | LAMINATED CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 2006-12-28 | — | — | US | disclosed |