SCHEMBL528221

SCHEMBL528221

C1CCC[C]2CCC(CCC1)CC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14937951 1.00 KMT2A (0.33) KMT2A
SCHEMBL3048851 1.00 KMT2A (0.33) KMT2A
SCHEMBL3892659 1.00 KMT2A (0.33) KMT2A
SCHEMBL3627702 1.00 KMT2A (0.33) KMT2A
SCHEMBL19358638 1.00 KMT2A (0.33) KMT2A
SCHEMBL23831120 1.00 KMT2A (0.33) KMT2A
SCHEMBL8862413 1.00 KMT2A (0.33) KMT2A
SCHEMBL1087219 1.00 KMT2A (0.33) KMT2A
SCHEMBL1088628 0.97 KMT2A (0.32) KMT2A
SCHEMBL262210 0.97 CA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012014127-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2012-02-02 WO disclosed
WO-2011161615-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2011-12-29 WO disclosed
WO-1993003719-A1 ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY ABBOTT LABORATORIES (US) 1993-03-04 WO disclosed