Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062142 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL841261 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8261356 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6737822 | 0.83 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL24769905 | 0.83 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL28040517 | 0.82 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10018238 | 0.81 | KDM4E (0.42) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL31735685 | 0.81 | POLB (0.45) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27641636 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6740724 | 0.80 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116456831-A | Biological insecticide | 坎纳尔地球科学有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-110087460-B | Bacillus thuringiensis RTI545 compositions and methods of use for benefiting plant growth and controlling plant pests | FMC 公司 | 2022-06-28 | — | — | CN | disclosed |
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| CN-1294121-C | Substituted anilide derivatives, intermediates thereof, agricultural and horticultural chemicals and their usage | NIHON NOHYAKU CO LTD (JP) | 2007-01-10 | — | — | CN | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
| CN-1512986-A | Substituted anilide derivatives, intermediates thereof, agricultural and horticultural chemicals and their usage | �ձ��ݶ�ũҩ��ʽ���� | 2004-07-14 | — | — | CN | disclosed |
| US-20040077557-A1 | Macrolide antibiotics | GLAXO GROUP LIMITED (GB) | 2004-04-22 | — | — | US | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | MEN1 2872/4885KMT2A 2302/4885SMN1; SMN2 3554/4885 |
| US-20060211636-A1 | Macrolide Antibiotics | IL1R1, MRPL12, RPS21 | MEN1 2872/4885KMT2A 2302/4885SMN1; SMN2 3554/4885 |
| US-20040077557-A1 | Macrolide antibiotics | MALT1, MRPL21, IL1R1 | MEN1 2870/4885KMT2A 2312/4885SMN1; SMN2 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.