Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313207 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL11911762 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL10237767 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL14937795 | 0.91 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL21527941 | 0.86 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL20005942 | 0.86 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL19995623 | 0.86 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| Hydrochloric Acid SCHEMBL21767825 | 0.83 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL2637713 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL3563911 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745040-A1 | AZABICYCLO(3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080382-A1 | AZABICYCLO (3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |