Sugi Predict

Sugi Predict / Compounds / SCHEMBL5283237

SCHEMBL5283237

SCHEMBL5283237

CC(C)(C)OC(=O)n1c(S(=O)(=O)N[C@H]2CCN(c3ccc4c(c3)CCN(C(=O)O)C4C(C)(C)C)C2=O)cc2ccc(Cl)cc21

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 16/20 0.47
▸ NR1H2 P55055 3/20 0.35
▸ GHSR Q92847 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5283242 0.89 F10 (0.45) F10GHSR
SCHEMBL4171262 0.84 F10 (0.47) F10NR1H2
SCHEMBL5279880 0.83 F10 (0.68) F10
SCHEMBL5288801 0.83 F10 (0.68) F10
SCHEMBL5242705 0.79 F10 (0.51) F10
SCHEMBL4179800 0.79 F10 (0.47) F10NR1H2
SCHEMBL4180969 0.77 F10 (0.65) F10
SCHEMBL5324751 0.77 F10 (0.65) F10
SCHEMBL4161614 0.72 F10 (0.63) F10
SCHEMBL5280236 0.72 F10 (0.69) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869010-A1 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2007-12-26 — — EP disclosed
WO-2006108709-A1 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2006-10-19 — — WO disclosed