Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142885 | 1.00 | CHRNA7 (0.44) | CHRNA7RXFP1KDM1ACA1CA2 | |
| SCHEMBL2138931 | 0.92 | RXFP1 (0.44) | CHRNA7RXFP1PTGER4LMNA | |
| SCHEMBL5275422 | 0.92 | RXFP1 (0.44) | CHRNA7RXFP1PTGER4LMNA | |
| SCHEMBL3399328 | 0.91 | CHRNA7 (0.35) | CHRNA7RXFP1CYP4F2CYP4A11 | |
| SCHEMBL314941 | 0.91 | CHRNA7 (0.35) | CHRNA7RXFP1CYP4F2CYP4A11 | |
| SCHEMBL315133 | 0.90 | CHRNA7 (0.33) | CHRNA7RXFP1CYP4F2CYP4A11 | |
| SCHEMBL315134 | 0.90 | CHRNA7 (0.33) | CHRNA7RXFP1CYP4F2CYP4A11 | |
| SCHEMBL2139532 | 0.89 | KDM1A (0.37) | CHRNA7RXFP1KDM1APTGER4CYP4F2 | |
| SCHEMBL314637 | 0.88 | CHRNA7 (0.32) | CHRNA7RXFP1CYP4F2CYP4A11 | |
| SCHEMBL314638 | 0.88 | CHRNA7 (0.32) | CHRNA7RXFP1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861411-A2 | NOVEL COMPOUNDS DERIVED FROM 5-THIOXYLOSE AND THERAPEUTIC USE THEREOF | LABORATOIRES FOURNIER S.A. (FR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100413-A9 | NOVEL COMPOUNDS DERIVED FROM 5-THIOXYLOSE AND THERAPEUTIC USE THEREOF | FOURNIER LAB SA (FR) | 2007-10-18 | — | — | WO | disclosed |
| WO-2006100413-A2 | NOVEL COMPOUNDS DERIVED FROM 5-THIOXYLOSE AND THERAPEUTIC USE THEREOF | LABORATOIRES FOURNIER S.A. (FR) | 2006-09-28 | — | — | WO | disclosed |