⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13226178 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL12307008 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL14433026 | 0.76 | PTGS1 (0.59) | — | |
| SCHEMBL127786 | 0.74 | — | — | |
| SCHEMBL40949 | 0.74 | — | — | |
| SCHEMBL978034 | 0.74 | — | — | |
| SCHEMBL14606380 | 0.74 | — | — | |
| SCHEMBL3090102 | 0.74 | — | — | |
| SCHEMBL407565 | 0.72 | — | — | |
| SCHEMBL1707333 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| US-5011928-A | Analgesic and antiinflammatory derivatives of 1-acyl-4-arylalkylpiperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMECEUTI COS S.A. (FAES) (ES) | 1991-04-30 | — | — | US | claimed |
| EP-0385043-A1 | New derivatives of 4-substituted piperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1990-09-05 | — | — | EP | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-5011928-A | Analgesic and antiinflammatory derivatives of 1-acyl-4-arylalkylpiperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMECEUTI COS S.A. (FAES) (ES) | 1991-04-30 | — | — | US | disclosed |
| EP-0385043-A1 | New derivatives of 4-substituted piperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1990-09-05 | — | — | EP | disclosed |