Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535310 | 0.82 | CA12 (0.56) | MAPTKMT2AALDH1A1HTTCA12 | |
| SCHEMBL4395475 | 0.82 | CA12 (0.56) | MAPTKMT2AALDH1A1HTTCA12 | |
| SCHEMBL1535326 | 0.81 | MAPT (0.52) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL10019901 | 0.78 | MAPT (0.51) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL3104512 | 0.76 | MAPT (0.68) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3099109 | 0.76 | MAPT (0.68) | MAPTKMT2AMEN1LMNARAB9A | |
| SCHEMBL9523524 | 0.75 | MAPT (0.61) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL9523516 | 0.75 | MAPT (0.61) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL3093420 | 0.75 | MAPT (0.67) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10121454 | 0.73 | MAPT (0.58) | MAPTKMT2AMEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339665-B1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX SA (FR) | 2007-12-19 | — | — | EP | claimed |