Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL28046702 | 0.90 | TSHR (0.36) | TSHR | |
| SCHEMBL5155580 | 0.85 | TSHR (0.48) | TSHR | |
| SCHEMBL7266590 | 0.77 | TSHR (0.40) | TSHR | |
| SCHEMBL701817 | 0.77 | TSHR (0.40) | TSHR | |
| Ammonia Solution, Strong SCHEMBL28010226 | 0.76 | TSHR (0.39) | TSHR | |
| SCHEMBL5155590 | 0.73 | — | — | |
| SCHEMBL7758299 | 0.73 | — | — | |
| SCHEMBL28237871 | 0.71 | TSHR (0.43) | TSHR | |
| Hydrochloric Acid SCHEMBL525599 | 0.71 | TSHR (0.43) | TSHR | |
| SCHEMBL27634162 | 0.71 | TSHR (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863446-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS OF LIOTHYRONINE AND METHODS OF MAKING AND USING THE SAME | King Pharmaceuticals Research and Development Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20060246133-A1 | Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same | CREDIT SUISSE AG | 2006-11-02 | — | — | US | disclosed |
| WO-2006105482-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS OF LIOTHYRONINE AND METHODS OF MAKING AND USING THE SAME | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. (US) | 2006-10-05 | — | — | WO | disclosed |