Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.65 |
| ▸ | FDPS | P14324 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2993814 | 0.95 | MEN1 (0.67) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL1716024 | 0.94 | MEN1 (0.76) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL294165 | 0.93 | MEN1 (0.65) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL2357881 | 0.92 | MEN1 (0.59) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL7742082 | 0.92 | MEN1 (0.59) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Sulfuric Acid SCHEMBL582395 | 0.92 | MEN1 (0.63) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Sulfuric Acid SCHEMBL27783819 | 0.90 | MEN1 (0.61) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL28478541 | 0.90 | MEN1 (0.65) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL4023088 | 0.90 | MEN1 (0.65) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL305739 | 0.89 | MEN1 (0.59) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108885367-B | Polarizing plate and liquid crystal display including the same | 株式会社LG化学 | 2021-09-07 | — | — | CN | disclosed |
| WO-2007006389-A1 | MIXTURE OF ONIUM ALKYL SULFONATES AND ONIUM ALKYL SULFITES | MERCK PATENT GMBH (DE) | 2007-01-18 | — | — | WO | disclosed |