Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316564 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| Cadaverine Tartrate SCHEMBL4326826 | 0.90 | SLC6A2 (0.54) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4324834 | 0.90 | SLC6A2 (0.54) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4324698 | 0.90 | SLC6A2 (0.51) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4327407 | 0.87 | SLC6A4 (0.54) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4324930 | 0.87 | SLC6A2 (0.61) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4317568 | 0.87 | SLC6A2 (0.61) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL4321553 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| Cadaverine Tartrate SCHEMBL4331820 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4CYP2D6KCNH2SLC6A3 | |
| SCHEMBL653143 | 0.82 | MBTPS1 (0.52) | SLC6A2SLC6A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756050-A1 | AMINOMETHYL-AZACYCLE DERIVATIVES AS INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118531-A1 | AMINOMETHYL-AZACYCLE DERIVATIVES AS INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | disclosed |