Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548575 | 1.00 | SCN4A (0.57) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL5025922 | 1.00 | SCN4A (0.57) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL14499008 | 0.87 | SCN4A (0.65) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL2633041 | 0.84 | SCN4A (0.53) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL9348338 | 0.84 | SCN4A (0.53) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL10547420 | 0.83 | SCN4A (0.61) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL12022873 | 0.83 | SCN4A (0.61) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL11106486 | 0.82 | SCN4A (0.47) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL12639964 | 0.82 | SCN4A (0.55) | SCN4ALMNAMAOAPTGS1LTA4H | |
| SCHEMBL5323614 | 0.80 | TAAR1 (0.50) | SCN4ALTA4HTAAR1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756107-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2006009789-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2006-01-26 | — | — | WO | claimed |
| CN-1277606-A | Substituted aryloxy alkyl amino triazines | BAYER AG (DE) | 2000-12-20 | — | — | CN | disclosed |
| EP-1034168-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | Bayer Aktiengesellschaft (DE) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999021841-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-06 | — | — | WO | disclosed |