Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.74 |
| ▸ | PDE4A | P27815 | 13/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046981 | 0.90 | PDE4B (0.77) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4045976 | 0.90 | PDE4B (0.77) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4051584 | 0.89 | PDE4B (0.75) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4047287 | 0.88 | PDE4B (0.89) | PDE4BPDE4APDE4DKMT2A | |
| SCHEMBL4047953 | 0.87 | PDE4B (0.72) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4045788 | 0.86 | PDE4B (0.72) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4049199 | 0.86 | PDE4B (0.85) | PDE4BPDE4APDE4DALDH1A1KMT2A | |
| SCHEMBL4046356 | 0.85 | PDE4B (1.00) | PDE4BPDE4APDE4DALDH1A1 | |
| SCHEMBL4046593 | 0.84 | PDE4B (0.69) | PDE4BPDE4APDE4DMEN1ALDH1A1 | |
| SCHEMBL4047110 | 0.84 | PDE4B (0.73) | PDE4BPDE4APDE4DMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819710-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058724-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-08 | — | — | WO | disclosed |