Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303190 | 0.93 | TLR8 (0.49) | TLR8NOS3NOS1NOS2SPNS2 | |
| SCHEMBL5818119 | 0.91 | TLR8 (0.51) | TLR8NOS3NOS1NOS2SPNS2 | |
| SCHEMBL5819373 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5810924 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5296554 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5304779 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5288827 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5304085 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5814869 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 | |
| SCHEMBL5286892 | 0.90 | SPNS2 (0.53) | LMNATLR8SPNS2CYP19A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006418-A1 | IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006131234-A1 | COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-12-14 | — | — | WO | disclosed |