Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701301 | 1.00 | KDM4E (0.56) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL598940 | 1.00 | KDM4E (0.56) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29701308 | 1.00 | KDM4E (0.56) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28546877 | 1.00 | KDM4E (0.56) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28031734 | 0.99 | KDM4E (0.55) | KDM4EMAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28177664 | 0.99 | KDM4E (0.55) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29431877 | 0.99 | KDM4E (0.55) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28910765 | 0.99 | KDM4E (0.57) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29701304 | 0.96 | MAPT (0.58) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28542188 | 0.96 | MAPT (0.58) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598873-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015904-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2012-02-02 | — | — | WO | disclosed |