Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529634 | 0.96 | MELK (0.75) | MELK | |
| Hydrochloric Acid SCHEMBL531164 | 0.90 | MELK (0.76) | MELK | |
| SCHEMBL529409 | 0.90 | MELK (0.81) | MELK | |
| SCHEMBL529485 | 0.90 | MELK (0.78) | MELK | |
| SCHEMBL12504812 | 0.88 | MELK (0.76) | MELK | |
| Hydrochloric Acid SCHEMBL531994 | 0.87 | MELK (0.76) | MELK | |
| SCHEMBL530855 | 0.86 | MELK (1.00) | MELK | |
| SCHEMBL530164 | 0.86 | MELK (1.00) | MELK | |
| SCHEMBL529532 | 0.86 | MELK (1.00) | MELK | |
| SCHEMBL12505175 | 0.86 | MELK (1.00) | MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |