Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.60 |
| ▸ | PPARD | Q03181 | 13/20 | 0.53 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959851 | 1.00 | PPARA (0.60) | PPARAPPARDPPARG | |
| SCHEMBL5361601 | 0.89 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL6149960 | 0.86 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL6151174 | 0.86 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL5797990 | 0.86 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL7023381 | 0.86 | PPARA (0.76) | PPARAPPARDPPARG | |
| SCHEMBL3956814 | 0.84 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5338861 | 0.84 | PPARA (0.75) | PPARAPPARDPPARG | |
| SCHEMBL4758109 | 0.84 | PPARA (0.75) | PPARAPPARDPPARG | |
| SCHEMBL15811673 | 0.84 | PPARA (0.75) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008156-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING A SUBSTITUTED PHENYLPROPIONIC ACID AS A FREE ACID AND AS TERT-BUTYL AMINE SALT THEREOF | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |
| EP-1638921-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110985-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
| EP-1458673-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR) | Astrazeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051821-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR) | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |