SCHEMBL529658

SCHEMBL529658

Fc1ccc(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29490721 1.00
Hydrochloric Acid SCHEMBL20455689 0.97 AHR (0.48)
SCHEMBL7402724 0.97 AHR (0.48)
Carbamic Acid SCHEMBL11787925 0.83 TSHR (0.48)
SCHEMBL29415157 0.79
SCHEMBL168149 0.79
SCHEMBL167260 0.79
SCHEMBL29415159 0.79
SCHEMBL6206442 0.79
SCHEMBL5317749 0.78 TP53 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221433071-U Device for preparing p-fluorobenzaldehyde by hydrolyzing p-fluorobenzyl chloride 浙江大洋生物科技集团股份有限公司 2024-07-30 CN claimed
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
CN-117884060-A System for preparing p-fluorobenzaldehyde by hydrolyzing p-fluorobenzyl chloride 浙江大洋生物科技集团股份有限公司 2024-04-16 CN claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
US-10781222-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-09-22 US claimed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US claimed
CN-107709506-B Surface treating agent containing perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2020-06-16 CN claimed
CN-108911944-A The preparation method of 2,4 dichloro fluorobenzene 浙江工业大学上虞研究院有限公司 2018-11-30 CN claimed
US-20180186820-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2018-07-05 US claimed
EP-3315579-A1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2018-05-02 EP claimed
EP-1436280-B1 A PROCESS FOR PREPARING 4-(HYDROXY)- 1,4']BIPIPERIDINYL-L'CARBOXYLIC ACID TERT-BUTYL ESTER ASTRAZENECA AB (SE) 2005-06-01 EP claimed
US-20050107428-A1 Chemical compounds ASTRAZENECA AB (SE) 2005-05-19 US claimed
US-20040235895-A1 Process for preparing 4-(hydroxy)-[1 4']bipiperidinyl-l'carboxylic acid tert-butyl ester ASTRAZENECA AB (SE) 2004-11-25 US claimed
EP-1478624-A1 CHEMICAL COMPOUNDS AstraZeneca AB (SE) 2004-11-24 EP claimed
EP-1436280-A1 A PROCESS FOR PREPARING 4-(HYDROXY)- 1,4']BIPIPERIDINYL-L'CARBOXYLIC ACID TERT-BUTYL ESTER AstraZeneca AB (SE) 2004-07-14 EP claimed
WO-2003068743-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2003-08-21 WO claimed
WO-2003031433-A1 A PROCESS FOR PREPARING 4-(HYDROXY)-[1,4']BIPIPERIDINYL-L'CARBOXYLIC ACID TERT-BUTYL ESTER ASTRAZENECA AB (SE) 2003-04-17 WO claimed
CN-1357524-A Prepn process of 2,4-dichlorofluorobenzene KUNSHAN SHUANGHE PHARMACEUTICA (CN) 2002-07-10 CN claimed
CN-1075949-A The 2,4 dichloro fluorobenzene synthesis technique NANJING MEDICINE INST (CN) 1993-09-08 CN claimed
CN-1070904-A The 2,4 dichloro fluorobenzene new process of production CHEMICAL GENERAL PLANT NO 2 JI (CN) 1993-04-14 CN claimed