Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.55 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777520 | 0.91 | HCRTR1 (0.60) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1776798 | 0.88 | HCRTR1 (0.58) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778492 | 0.88 | HCRTR1 (0.63) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778258 | 0.87 | HCRTR1 (0.67) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778331 | 0.87 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1778335 | 0.87 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1777479 | 0.87 | HCRTR1 (0.57) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777808 | 0.85 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1777806 | 0.85 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL1776564 | 0.85 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406897-B1 | COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2007-03-14 | — | — | EP | claimed |