Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946866 | 1.00 | SLC22A2 (0.50) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL2536293 | 0.82 | SLC22A2 (0.46) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL29047106 | 0.78 | SLC22A2 (0.52) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL21712133 | 0.76 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL4137129 | 0.75 | KMT2A (0.44) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL354415 | 0.74 | SLC22A2 (0.43) | SLC22A2SLC47A1MAPTALDH1A1NPC1 | |
| SCHEMBL3813603 | 0.73 | KMT2A (0.48) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL660251 | 0.73 | SLC22A2 (0.52) | SLC22A2SLC47A1MAPTKMT2AMEN1 | |
| SCHEMBL353492 | 0.73 | SLC22A2 (0.46) | SLC22A2SLC47A1MAPTALDH1A1NPC1 | |
| SCHEMBL659876 | 0.73 | SLC22A2 (0.58) | SLC22A2SLC47A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028022-A2 | NOVEL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |