Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644162 | 0.88 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644165 | 0.88 | KCNH2 (0.71) | KCNH2GCK | |
| SCHEMBL2644486 | 0.83 | KCNH2 (0.77) | KCNH2GCK | |
| SCHEMBL2644484 | 0.83 | KCNH2 (0.77) | KCNH2GCK | |
| SCHEMBL2644718 | 0.83 | KCNH2 (0.70) | KCNH2GCK | |
| SCHEMBL2644719 | 0.83 | KCNH2 (0.70) | KCNH2GCK | |
| SCHEMBL2645966 | 0.82 | KCNH2 (0.76) | KCNH2GCK | |
| SCHEMBL2644707 | 0.82 | KCNH2 (0.76) | KCNH2GCK | |
| SCHEMBL2645964 | 0.82 | KCNH2 (0.76) | KCNH2GCK | |
| SCHEMBL2644709 | 0.82 | KCNH2 (0.76) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572670-B1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | EP | claimed |