SCHEMBL5303809

SCHEMBL5303809

CC(C)[C@H](N)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.57
MEN1 O00255 9/20 0.57
GAA P10253 2/20 0.56
LMNA P02545 3/20 0.56
MAPT P10636 7/20 0.53
ALDH1A1 P00352 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
NPC1 O15118 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 1/20 0.51
POLB P06746 2/20 0.50
TGM2 P21980 1/20 0.50
MYOC Q99972 1/20 0.50
MMP9 P14780 1/20 0.49
HTR1E P28566 1/20 0.49
S1PR3 Q99500 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27676029 1.00 KMT2A (0.57) KMT2AMEN1GAALMNAMAPT
SCHEMBL30631607 0.89 KMT2A (0.56) KMT2AMEN1GAALMNAMAPT
SCHEMBL9259881 0.87 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
SCHEMBL10914836 0.87 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
SCHEMBL987822 0.87 KMT2A (0.61) KMT2AMEN1GAALMNAMAPT
Hydrochloric Acid SCHEMBL1895198 0.86 KMT2A (0.59) KMT2AMEN1GAALMNAMAPT
SCHEMBL5582019 0.85 KMT2A (0.59) KMT2AMEN1GAALMNAMAPT
SCHEMBL29111851 0.85 KMT2A (0.62) KMT2AMEN1GAALMNAMAPT
SCHEMBL29111764 0.85 KMT2A (0.62) KMT2AMEN1GAALMNAMAPT
SCHEMBL29111760 0.85 KMT2A (0.62) KMT2AMEN1GAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303360-B1 CULTURING SPHINGOMONAS; MOLECULAR HYBRIDIZATION; GENETIC ENGINEERING; HYDROLYZES ANILIDES OF ALANINE, GLYCINE, LEUCINE, GLUTAMIC ACID, ASPARTIC ACID, LYSINE, ISOLEUCINE, AND VALINE NOVOZYMES BIOTECH, INC, 2001-10-16 US claimed
US-6184020-B1 AMINO ACID AND NUCLEOTIDE SEQUENCE; FOR PRODUCTION OF PROTEIN HYDROLYSATES USED AS FLAVORINGS IN FOODS NOVO NORDISK BIOTECH, INC. 2001-02-06 US claimed
JP-57056446-A None JP disclosed
CN-122038358-A Aminopeptidase APs8-A297V, aminopeptidase APs8-A599V and application thereof 中国海洋大学 2026-05-15 CN disclosed
EP-4735111-A1 SINGLE-DOMAIN ANTIBODY FOR INHIBITION OF NEUTROPHIL ELASTASE ACTIVITY Université de Liège (BE) 2026-05-06 EP disclosed
EP-4596689-A1 ENZYME AGENT AND USE THEREOF Amano Enzyme Inc. (JP) 2025-08-06 EP disclosed
CN-120092086-A Enzyme agent and application thereof 天野酶制品株式会社 2025-06-03 CN disclosed
WO-2025003495-A1 SINGLE-DOMAIN ANTIBODY FOR INHIBITION OF NEUTROPHIL ELASTASE ACTIVITY Université de Liège (BE) 2025-01-02 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024071388-A1 ENZYME AGENT AND USE THEREOF 天野エンザイム株式会社 2024-04-04 WO disclosed
US-11946079-B2 Method for producing a protein hydrolysate using an endopeptidase and a carboxypeptidase NOVOZYMES A/S (DK) 2024-04-02 US disclosed
EP-0906091-A1 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1999-04-07 EP disclosed
WO-1998024806-A2 SUBSTITUTED OXADIAZOLE, THIADIAZOLE AND TRIAZOLE SERINE PROTEASE INHIBITORS CORTECH, INC. (US) 1998-06-11 WO disclosed
WO-1997047299-A1 AMIDINO AND GUANIDINO HETEROCYCLIC PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1997-12-18 WO disclosed
WO-1997036580-A1 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1997-10-09 WO disclosed
EP-0724647-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NeXstar Pharmaceuticals, Inc. (US) 1996-08-07 EP disclosed
WO-1995007364-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NEXSTAR PHARMACEUTICALS, INC. (US) 1995-03-16 WO disclosed
CN-88100378-A New peptidase inhibitors 1988-10-05 CN disclosed
CN-86101268-A The preparation method of new peptidase inhibitors 1987-02-04 CN disclosed
JP-S5756446-A SUCCINYL-L-TYROSYL-L-LEUCYL-L-VALINE-P-NITROANILIDE AND ITS PREPARATION DAI ICHI PURE CHEM CO LTD 1982-04-05 JP disclosed