Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810465 | 0.95 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5303543 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5818404 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5301172 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5286033 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5810925 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5305269 | 0.93 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5327172 | 0.80 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5301081 | 0.78 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5304124 | 0.78 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006418-A1 | IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-01-18 | — | — | WO | disclosed |