Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 20/20 | 0.72 |
| ▸ | LCK | P06239 | 8/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LYN | P07948 | 1/20 | 0.71 |
| ▸ | BTK | Q06187 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967290 | 0.88 | TNK2 (0.84) | TNK2LCKABL1LYNBTK | |
| SCHEMBL17859385 | 0.84 | TNK2 (0.89) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2977801 | 0.84 | TNK2 (0.89) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2965872 | 0.84 | TNK2 (1.00) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2974800 | 0.84 | TNK2 (1.00) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2967661 | 0.84 | TNK2 (1.00) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2977473 | 0.84 | TNK2 (1.00) | TNK2LCKABL1LYNBTK | |
| SCHEMBL13202746 | 0.84 | TNK2 (1.00) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2963954 | 0.83 | TNK2 (0.82) | TNK2LCKABL1LYNBTK | |
| SCHEMBL2975441 | 0.83 | TNK2 (0.89) | TNK2LCKABL1LYNBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768986-A2 | FURANOPYRIMIDINES | Amgen Inc. (US) | 2007-04-04 | — | — | EP | claimed |
| WO-2006004658-A2 | FURANOPYRIMIDINES | AMGEN INC. (US) | 2006-01-12 | — | — | WO | claimed |