Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.74 |
| ▸ | PNLIP | P16233 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clioxanide SCHEMBL636665 | 0.86 | POLB (1.00) | POLBNLRP3PNLIPKMT2AMEN1 | |
| Clioxanide SCHEMBL29358452 | 0.86 | POLB (1.00) | POLBNLRP3PNLIPKMT2AMEN1 | |
| SCHEMBL26176577 | 0.78 | POLB (0.76) | POLBNLRP3KMT2AMEN1HSPD1 | |
| SCHEMBL20413309 | 0.76 | POLB (0.79) | POLBNLRP3PNLIPKMT2AMEN1 | |
| SCHEMBL20413314 | 0.73 | POLB (0.67) | POLBNLRP3KMT2AMEN1NPC1 | |
| SCHEMBL14223805 | 0.72 | POLB (0.72) | POLBNLRP3PNLIPKMT2AMEN1 | |
| SCHEMBL10428048 | 0.71 | P2RX1 (0.57) | PNLIPKMT2AMEN1HTTGAA | |
| Resorantel SCHEMBL1027956 | 0.71 | TP53 (0.61) | KMT2AMEN1HTTNPC1ALDH1A1 | |
| SCHEMBL14223829 | 0.71 | POLB (0.67) | POLBNLRP3PNLIPKMT2AMEN1 | |
| Resorantel SCHEMBL11209389 | 0.70 | TP53 (0.59) | KMT2AMEN1HTTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041584-A2 | IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041593-A2 | ANTI-SCARRING DRUG COMBINATIONS AND USE THEREOF | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |