Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309940 | 0.84 | MEN1 (0.49) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5311723 | 0.82 | HIF1A (0.48) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5308730 | 0.79 | KMT2A (0.44) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL2926999 | 0.75 | MEN1 (0.50) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5309948 | 0.74 | MEN1 (0.61) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5305797 | 0.73 | EGLN3 (0.52) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5309020 | 0.73 | SERPINE1 (0.50) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5312251 | 0.73 | MEN1 (0.48) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5312400 | 0.73 | MEN1 (0.48) | MEN1KMT2ARXFP1RAB9ANPC1 | |
| SCHEMBL5312534 | 0.72 | EGLN1 (0.46) | MEN1KMT2ARXFP1EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |