Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607031 | 0.90 | MEN1 (0.66) | CYP2C19GAATSHRTMEM97SIGMAR1 | |
| SCHEMBL24673292 | 0.90 | MEN1 (0.66) | CYP2C19GAATSHRTMEM97SIGMAR1 | |
| SCHEMBL2954213 | 0.85 | TSHR (0.63) | CYP2C19GAATSHRMEN1KMT2A | |
| SCHEMBL24091701 | 0.85 | TMEM97 (0.60) | CYP2C19TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL22014628 | 0.84 | MEN1 (0.80) | CYP2C19GAATSHRTMEM97SIGMAR1 | |
| SCHEMBL31443404 | 0.84 | SMN1; SMN2 (0.58) | CYP2C19GAATSHRMEN1KMT2A | |
| SCHEMBL6237772 | 0.83 | MEN1 (0.61) | CYP2C19GAATSHRMEN1KMT2A | |
| SCHEMBL3970912 | 0.83 | MEN1 (0.76) | CYP2C19GAATSHRHTR2CMEN1 | |
| SCHEMBL4814264 | 0.83 | MEN1 (0.76) | CYP2C19GAATSHRHTR2CMEN1 | |
| SCHEMBL7393652 | 0.83 | MEN1 (0.76) | CYP2C19GAATSHRHTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039578-A1 | IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |