SCHEMBL5309233

SCHEMBL5309233

O=C(O)c1ccc(N2CCCN(C(=O)c3ccccc3C(F)(F)F)C2)nn1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 15/20 0.60
DCTPP1 Q9H773 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5310991 0.88 SCD (0.61) SCDDCTPP1
SCHEMBL935839 0.87 SCD (0.77) SCDDCTPP1
SCHEMBL5314080 0.87 SCD (0.55) SCDDCTPP1
SCHEMBL5309844 0.86 SCD (0.49) SCDDCTPP1
SCHEMBL5312647 0.86 SCD (0.80) SCDDCTPP1
SCHEMBL5309708 0.85 SCD (0.65) SCDDCTPP1
SCHEMBL5309961 0.85 SCD (0.61) SCDDCTPP1
SCHEMBL5309076 0.85 SCD (0.43) SCDDCTPP1
SCHEMBL5308957 0.85 SCD (0.55) SCDDCTPP1
SCHEMBL5311758 0.84 SCD (0.71) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046867-A2 PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2007-04-26 WO disclosed