Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.37 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.37 |
| ▸ | MAP3K2 | Q9Y2U5 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306427 | 0.91 | SCD (0.55) | SCDDDR1MAPK11MAPK14DDR2 | |
| SCHEMBL5312248 | 0.89 | SCD (0.56) | SCD | |
| SCHEMBL5309646 | 0.86 | SCD (0.55) | SCD | |
| SCHEMBL5312492 | 0.85 | EGLN1 (0.42) | SCDNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL5309578 | 0.83 | SCD (0.48) | SCDNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL5312612 | 0.82 | SCD (0.40) | SCDNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL5314056 | 0.82 | PRKAA2 (0.45) | SCDNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5312057 | 0.81 | SCD (0.52) | SCDMAPK14 | |
| SCHEMBL5310962 | 0.81 | SCD (0.57) | SCD | |
| SCHEMBL5310977 | 0.80 | SCD (0.56) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |