Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | FYN | P06241 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720098 | 0.83 | HSD17B10 (0.62) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL6720093 | 0.83 | HSD17B10 (0.62) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL10108985 | 0.79 | HSD17B10 (0.61) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL10124214 | 0.78 | HSD17B10 (0.64) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL13644181 | 0.76 | KDM4E (0.70) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL12608313 | 0.75 | HSD17B10 (0.52) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL13987942 | 0.74 | HSD17B10 (0.75) | HSD17B10KDM4ETDP1POLBMAPT | |
| SCHEMBL24666864 | 0.73 | HSD17B10 (0.66) | HSD17B10KDM4ETDP1POLBMAPT | |
| Methyldopa SCHEMBL34003 | 0.73 | KDM4E (1.00) | HSD17B10KDM4ETDP1POLBMAPT | |
| Methyldopa (Racemic) SCHEMBL196981 | 0.73 | KDM4E (1.00) | HSD17B10KDM4ETDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042848-A2 | PROCESS FOR THE PREPARATION OF CARBIDOPA | EGIS GYÓGYSZERGYÁR (HU) | 2007-04-19 | — | — | WO | disclosed |