Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTB | P49356 | 4/20 | 0.86 |
| ▸ | FNTA | P49354 | 3/20 | 0.86 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.86 |
| ▸ | EGFR | P00533 | 1/20 | 0.85 |
| ▸ | FYN | P06241 | 1/20 | 0.85 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.85 |
| ▸ | DRD2 | P14416 | 1/20 | 0.85 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.85 |
| ▸ | TACR2 | P21452 | 1/20 | 0.85 |
| ▸ | MC5R | P33032 | 1/20 | 0.85 |
| ▸ | DRD3 | P35462 | 1/20 | 0.85 |
| ▸ | MC3R | P41968 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723220 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL17534944 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL2723214 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL14640162 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL16111867 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL2723216 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL1683561 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL5310552 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL17534946 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN | |
| SCHEMBL16111866 | 1.00 | FNTB (0.86) | FNTBFNTAPGGT1BEGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |