Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | STAT1 | P42224 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310937 | 1.00 | MAPT (0.72) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17693070 | 0.91 | MAPT (0.81) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30568701 | 0.90 | KDM1A (0.76) | MAPTTP53KMT2AMEN1KDM4E | |
| SCHEMBL3242114 | 0.87 | MEN1 (0.78) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30568744 | 0.85 | KDM1A (0.79) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9607194 | 0.84 | MEN1 (0.78) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2839312 | 0.83 | MEN1 (1.00) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2849002 | 0.83 | MEN1 (1.00) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2842894 | 0.82 | KDM4E (0.81) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2842891 | 0.82 | KDM4E (0.81) | MAPTTP53KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |