SCHEMBL531155

SCHEMBL531155

O=C(CCCCCCCCCCCCC(=O)Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.73
CTNNB1 P35222 1/20 0.73
TDP1 Q9NUW8 1/20 0.55
GAA P10253 1/20 0.54
MGLL Q99685 2/20 0.54
PTPN7 P35236 1/20 0.54
PTPN12 Q05209 1/20 0.54
PTPN22 Q9Y2R2 1/20 0.54
KMT2A Q03164 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
MAPT P10636 2/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
EGFR P00533 2/20 0.50
ERBB2 P04626 2/20 0.50
PKM P14618 1/20 0.50
ALDH1A1 P00352 2/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CES2 O00748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL530771 1.00 BCL9 (0.73) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL570540 1.00 BCL9 (0.73) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL7079988 1.00 BCL9 (0.73) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL531007 0.98 BCL9 (0.76) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL3919600 0.95 BCL9 (0.76) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL12189868 0.94 BCL9 (0.66) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL16915260 0.94 BCL9 (0.66) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL531330 0.94 BCL9 (0.66) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL29164403 0.94 BCL9 (0.66) BCL9CTNNB1TDP1GAAMGLL
SCHEMBL31758269 0.94 BCL9 (0.66) BCL9CTNNB1TDP1GAAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313794-B1 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RES FOUNDATION INC (US) 2006-11-29 EP claimed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US claimed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP claimed
US-6503538-B1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2003-01-07 US claimed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO claimed
EP-2413909-B1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S UNIV CORNELL (US) 2016-11-30 EP disclosed
US-8993686-B2 Multiamino acid-based poly(ester amide)s CORNELL UNIVERSITY (US) 2015-03-31 US disclosed
US-20120123064-A1 Multiamino Acid-Based Poly(Ester Amide)s CORNELL UNIVERSITY (US) 2012-05-17 US disclosed
EP-2413909-A1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S Cornell University (US) 2012-02-08 EP disclosed
WO-2010114601-A1 MULTIAMINO ACID-BASED POLY (ESTER AMIDE)S CORNELL UNIVERSITY (US) 2010-10-07 WO disclosed
US-7408018-B2 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. (US) 2008-08-05 US disclosed
US-7304122-B2 Useful as carriers of drugs or other bioactive substances; polymers can be linked, intermixed, or a combination thereof, to one or more drugs CORNELL RESEARCH FOUNDATION, INC. (US) 2007-12-04 US disclosed
US-20070027293-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2007-02-01 US disclosed
EP-1313794-B1 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RES FOUNDATION INC (US) 2006-11-29 EP disclosed
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2004-04-01 US disclosed
WO-2003062298-A1 CO-POLY(ESTER AMIDE) AND CO-POLY(ESTER URETHANE) COMPOSITIONS WHICH EXHIBIT BIODEGRADABILITY, METHODS FOR MAKING SAME AND USES FOR SAME POLYRAVA LLC (US) 2003-07-31 WO disclosed
EP-1313794-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2003-05-28 EP disclosed
US-6503538-B1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes CORNELL RESEARCH FOUNDATION, INC. 2003-01-07 US disclosed
WO-2002018477-A2 ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES CORNELL RESEARCH FOUNDATION, INC. (US) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063606-A1 Elastomeric functional biodegradable copolyester amides and copolyester urethanes PUF60, UROD, UBE2I BCL9 4755/4885CTNNB1 4778/4885TDP1 1135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.