SCHEMBL5311586

SCHEMBL5311586

Cc1c(CCCC(=O)O)cccc1C(=O)c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.47
FFAR4 Q5NUL3 2/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SUCNR1 Q9BXA5 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ABCB11 O95342 1/20 0.39
LMNA P02545 1/20 0.39
PTGS1 P23219 1/20 0.39
ADORA1 P30542 1/20 0.39
PTGS2 P35354 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236594 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
SCHEMBL11226222 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
SCHEMBL11225037 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
SCHEMBL11230471 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
SCHEMBL11234825 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
SCHEMBL11223554 0.95 NR4A1 (0.44) NR4A1FFAR4MRGPRX4
Hydrochloric Acid SCHEMBL11544689 0.94 NR4A1 (0.43) NR4A1FFAR4MRGPRX4
SCHEMBL11858604 0.92 NR4A1 (0.49) NR4A1FFAR4MRGPRX4ALDH1A1KDM4E
SCHEMBL11222105 0.90 NR4A1 (0.43) NR4A1FFAR4MRGPRX4ALDH1A1KDM4E
SCHEMBL11863466 0.87 SLC16A3 (0.46) MRGPRX4ALDH1A1KDM4ERAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3995056-A Butyric acid derivatives for treating pain and inflammation ROUSSEL-UCLAF (FR) 1976-11-30 US claimed
US-3931302-A ANTIINFLAMMATORY, ANALGESIC ROUSSEL-UCLAF (FR) 1976-01-06 US claimed
WO-2014176460-A1 METHODS OF TREATING BEHAVIORIAL AND/OR MENTAL DISORDERS CHAU DAVID T (US) 2014-10-30 WO disclosed
US-8486922-B2 Composition CHEN CHIEN-HUNG (TW) 2013-07-16 US disclosed
US-20120183600-A1 NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS CHEN CHIEN-HUNG (US) 2012-07-19 US disclosed
WO-2007044184-A1 WATER SOLUBLE PHOTOINITIATOR ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed
US-4337353-A ANALGESICS, ANTIINFLAMMATORY AGENTS ROUSSEL UCLAF (FR) 1982-06-29 US disclosed
US-3995056-A Butyric acid derivatives for treating pain and inflammation ROUSSEL-UCLAF (FR) 1976-11-30 US disclosed
US-3931302-A ANTIINFLAMMATORY, ANALGESIC ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed